Quick Answer
Yes. ChatGPT's Code Interpreter handles files directly. Others need copy-paste.
Detailed Answer
ChatGPT Plus lets you upload Excel/CSV files and run Python analysis directly—create charts, find patterns, clean data. Claude and Gemini can analyze data you paste but cannot upload files the same way. Gemini integrates with Google Sheets natively. For serious data analysis, ChatGPT's Code Interpreter is the standout feature.
Find Your Own Answer
The best way to decide is to try them yourself. Council lets you compare multiple AI responses to the same question.